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Director's Letter
 Genomics, the study of individual genetic structure including the study of how genes interact between them and with the environment, has the potential to revolutionise the practise of medicine. This revolution is what we call Individualized Medicine.
Individualized Medicine uses Genomic information to improve diagnosis of the disease as well as its prevention and treatment. Its goal is to achieve the best clinical results through the knowledge of the individual genetic profile together with other factors such as familiar background or medical history.
With Individualised Medicine, either physicians or patients could take decisions being wellinformed about the best treatment and optimal dose to achieve the heightened levels of effectiveness with the best tolerance.
Pharmacogenomics is the key that allows to anticipate the response of a medicine based on the individual's genetic constitution as well as to design new medicines regarding genetic information. However, the great challenge is to translate this knowledge, in constant development, to clinical practise.
It is not an easy issue, as not only a new way of thinking is required: individualisation, but also medical practice would be more complex. Not to forget the strong implications that such a revolution will have on numerous areas such as Economy, Law and Politics.
Supporting the incorporation of Individualised Medecine to our Health System is exactly the area where the activity of the Roche Institute is set. Since it was constituted in 2004, the purpose of Roche Institute is to promote the approach of Individualized Medicine to our society through activities such as: education of health professionals and the support of multidisciplinary work in order to facilitate the knowledge translation from Genomic Research to Clinical Research, thus facilitating the debate and consensus regarding legal, ethical and economical issues as essential to allow Individualized Medicine to become a reality in our National Health System.
Jaime del Barrio
Roche Institute Managing Director.
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